LentiBrite alpha-actinin-GFP Lentiviral Biosensor

Catalog number: 17-10156
Brand: Merck
Packing: 1 Vials
Price: € 523.00
Expected delivery time: 7 days
Quantity:

Product specifications for - LentiBrite alpha-actinin-GFP Lentiviral Biosensor

Overview: 
Product group: DNA / RNA / Vectors
Category: Plasmid / vector
Properties: 
  Research Use Only
UNSPSC: 41106600
Storage instructions: Storage and HandlingLentivirus is stable for at least 4 months from date of receipt when stored at -80-¦C. After first thaw, place immediately on ice and freeze in working aliquots at -80-¦C. Frozen aliquots may be stored for at least 2 months. Further freeze/thaws may result in decreased virus titer and transduction efficiency. IMPORTANT SAFETY NOTEReplication-defective lentiviral vectors, such as the 3rd Generation vector provided in this product, are not known to cause any diseas
Scientific information: 
Scientific info: Migration of cells requires engagement of sites of extracellular matrix contact (focal adhesions) with the actin cytoskeleton. Contractile force is further generated when the actin microfilaments develop into stress fibers by bundling in an anti-parallel fashion and recruiting myosin II. A key component of stress fibers is the spectrin-related protein, alpha-actinin, which directly links actin microfilaments and also couples them to focal adhesions. Imaging of live cells containing alpha-actinin fused with fluorescent proteins has provided key insights into the dynamic mechanisms of stress fiber assembly and adaptation to strain.EMD Millipore’s LentiBrite alpha-actinin-GFP lentiviral particles provide bright fluorescence and precise localization to enable live cell analysis of focal adhesion dynamics in difficult-to-transfect cell types.
Additional information: 
Synonyms: 17-10156; Merck (Millipore)