Caspase-1 (mouse) ELISA Kit
AG-45B-0002
Overview
- SupplierAdipoGen Life Sciences
- Product NameCaspase-1 (mouse) ELISA Kit
- Delivery Days Customer10
- ApplicationsELISA
- Assay Detection Range0.15ng/ml to 10ng/ml
- Assay Sensitivity33pg/ml
- Assay SpecificityDetects mouse caspase-1 (proform as well as p10 and p20 domain). Does not detect human caspase-1.
- CertificationResearch Use Only
- Scientific DescriptionCaspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and interleukin-18 (IL-18) and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3/NALP3 responds to a variety of agonists including crystals. This Caspase-1 (mouse) ELISA Kit can be used to measure caspase-1 (mouse) in cell culture supernatants, serum and plasma. It is a quantitative detection method, alternative to Western blotting to measure caspase-1 secretion. - ELISA Assay. Detects mouse caspase-1 (proform as well as p10 and p20 domain). Does not detect human caspase-1. Colorimetric assay. Sample Types: Cell Culture Supernatant, Plasma, Serum. Range: 0.15ng/ml to 10ng/ml. Sensitivity: 33pg/ml. Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and interleukin-18 (IL-18) and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3/NALP3 responds to a variety of agonists including crystals. This Caspase-1 (mouse) ELISA Kit can be used to measure caspase-1 (mouse) in cell culture supernatants, serum and plasma. It is a quantitative detection method, alternative to Western blotting to measure caspase-1 secretion.
- ReactivityMouse
- Storage Instruction2°C to 8°C
- UNSPSC41116133